l 个人简介：
陈飞，工学博士，南京师范大学生命科学学院副教授，硕士研究生导师，兼任南京市特色生物资源功能成分开发工程研究中心副主任。主要从事药用植物活性成分的生物合成与调控及其种质资源的开发保护工作。主持国家自然科学基金、国家重点研发计划子课题、中央本级重大增减支项目课题等项目。以第一或通讯作者在Industrial Crops & Products、Microbiological Research、Plant Physiology and Biochemistry、Bioresource Technology等专业期刊发表论文20多篇。第一发明人申请发明专利4件、软著3项，起草江苏省地方标准《茅苍术工厂化育苗技术规程》。相关研究成果获得江苏省高校自然科学研究成果奖一等奖和江苏省分析测试协会科学技术奖二等奖。学术兼职包括担任Frontiers in Microbiology杂志“Interactions Between Medicinal Plants and Microbes: From Molecules to Ecosystem”客座主编、中国中药协会中药生态农业专业委员会委员、江苏省“双创计划”科技副总等。
l 学习、工作简历：
201806—至今 南京师范大学 生命科学学院 副教授
201308—201806 南京师范大学 生命科学学院 讲师
200809—201306 南京工业大学 生物化工/发酵工程（硕博连读） 工学博士
l 主要研究方向：
药用植物活性成分的生物合成与调控
珍稀药用植物种质资源的开发与保护
微生物合成高附加值生化产品的代谢调控
l 主持科研项目：
(1) 国家重点研发计划子课题：粮油及制品的食品安全快检方法筛查与质量再评估研究，2018YFC1603404，201812—202112.
(2) 中央本级重大增减支项目“名贵中药资源可持续利用能力建设项目”课题：茅苍术microRNA在茎提前发育过程中促进倍半萜高效合成的调控机制研究，2060302-2003-06，202001—202312.
(3) 国家自然科学基金青年基金项目：茅苍术细胞中3种主要倍半萜的合成途径探讨及其代谢调控研究，21406119，201501—201712.
(4) 江苏省高校自然科学研究项目：基于蛋白组学探讨茅苍术中三种主要倍半萜的代谢机制，14KJB180009，201408—201612.
(5) 横向科研项目：生物法合成非天然氨基酸系列产品的关键工艺开发，ZK-2025-kf-88，202503—202706. (第二主持)
(6) 横向科研项目：茅苍术活性倍半萜单体制备的产业化关键技术研究，科技开发18-077，201810—201912.
(7) 横向科研项目：苍术的生态种植技术示范与课程开发，ZK-2024-fw-59，202403—202503.
(8) 横向科研项目：特色生物资源功能性活性成分，科技服务22-017，202203—202212.
l 论文发表：
(1) Xu Han#, Kao-Ping Zhang#, Zi-Ang Zhang, Chuan-Chao Dai, Fei Chen*. Endophytes drive the biosynthesis and accumulation of sesquiterpenoids in Atractylodes lancea (Thunb.) DC. Industrial Crops & Products, 2025, 225, 120528.
(2) Meng Tang, Xu-Ying Yao, Jia-Yan Xu, Jia-Yun Wu, Kai Sun, Chuan-Chao Dai, Fei Chen*. Auxin signaling activated by endophytic Cross-Kingdom synthetic microbiota improves the quality of Atractylodes chinensis. Microbiological Research, 2025, 301, 128312.
(3) Zi-Ang Zhang, Xin-Yao Xue, Jia-Yun Wu, Xuan Zhao, Hao Zhang, Kai Sun, Chuan-Chao Dai, Fei Chen*. CYP71P2 regulated by MYB44 modulates oxygenated sesquiterpenoids biosynthesis in Atractylodes lancea. Plant Physiology and Biochemistry, 2025, 229, 110700.
(4) Zi-Ang Zhang, Meng Tang, Jing Yang, Qi-Yin Yang, Chuan-Chao Dai, Fei Chen*. Highly efficient production of prodigiosin from corn stover hydrolysate in Serratia marcescens mutant RZ 21-6C generated by atmospheric and room‑temperature plasmas mutagenesis. Bioprocess and Biosystems Engineering, 2025, 48:799–816.
(5) Feng-Yan Kuang#, De-Jun Hu#, Lu Wang, Fei Chen*, Guang-Ping Lv*. Ti-based MOF nanosheets as a mass spectrometry imaging matrix for low molecular weight compounds to reveal the spatiotemporal content changes of hepatotoxic components during the processing of Polygonum multiflorum. Analyst, 2025, 150, 120.
(6) Si-Si Jia, Zi-Wei Han, Hui-Yang Wang, Yv-Jie Wu, Mei-Juan Zhao, Hong-Wei Qiu, He-He Li, Fei Chen*, Guang-Ping Lv*. Characterization and discrimination of polysaccharides from three Atractylodes spp. based on multiple structural information. Carbohydrate Research, 2025, 558, 109694.
(7) Jie Yuan, Wen-Na Zhao, Xiao-Qing Wu, Cheng Ji, Lei Wang, Cong Xu, Dong Liang, Bing Feng, Guo-Peng Zhu, Fei Chen, Ji-Dong Wang*, Yong-Chun Zhang*. AMF modulation of sweet potato plant performance and rhizosphere microecology depends on soil potassium availability: shared and differential strategies. Plant and Soil, 2025, Doi: 10.1007/s11104-025-08023-z.
(8) Kao-Ping Zhang#, Song Yang#, Xu Han, Fei Chen*. Soil C:N:P stoichiometry regulates the response of soil bacterial community composition and putative functions to coastal reclamation. Journal of Soils and Sediments, 2024, 24:819–828.
(9) Chun‑Yan Wang, Xu Han, Fei Chen*, Chuan‑Chao Dai*. The microRNA analysis of sesquiterpenoids biosynthesis by Atractylodes lancea (Thunb.) DC. with early stem growth mutation. Plant Cell, Tissue and Organ Culture, 2024, 156, 3.
(10) Ling-Sen Cao, Di Wang, Chun-Yan Wang, Wei Zhang, Fei Chen, Yaseen Ullah, Kai Sun*, Chuan-Chao Dai*. Endophytic Pseudomonas fluorescens relieves intraspecific allelopathy of Atractylodes lancea by reducing ethylene transportation. BMC Plant Biology, 2024, 24, 1095.
(11) Ying-Yue Zhang, Mei-Juan Zhao, Chun-Yao Liu, Kai Ma, Tian-Yu Liu, Fei Chen, Li-Na Wu, De-Jun Hu*, Guang-Ping Lv*. Comparison of two commercial methods with a UHPLC-MS/MS method for the determination of multiple mycotoxins in cereals. Food Chemistry, 2023, 406, 135056.
(12) Di Wang, Fei Chen*, Chun‑Yan Wang, Xu Han, Chuan-Chao Dai*. Early stem growth mutation alters metabolic flux changes enhance sesquiterpenoids biosynthesis in Atractylodes lancea (Thunb.) DC. Plant Cell, Tissue and Organ Culture, 2022, 149:467–483.
(13) Hu-Rong Yang, Jie Yuan, Lian-Hong Liu, Wei Zhang, Fei Chen, Chuan-Chao Dai*. Endophytic Pseudomonas fluorescens induced sesquiterpenoid accumulation mediated by gibberellic acid and jasmonic acid in Atractylodes macrocephala Koidz plantlets. Plant Cell, Tissue and Organ Culture, 2019, 138:445–457.
(14) Jia-Yu Zhou, Kai Sun, Fei Chen, Jie Yuan, Xia Li, Chuan-Chao Dai*. Endophytic Pseudomonas induces metabolic flux changes that enhance medicinal sesquiterpenoid accumulation in Atractylodes lancea. Plant Physiology and Biochemistry, 2018, 130:473–481.
(15) Cheng-Gang Ren, Fei Chen, Chuan-Chao Dai*. Fungal endophyte protects Atractylodes lancea from root rot caused by Fusarium oxysporum. Plant Pathology, 2017, 66:223–229.
(16) Fei Chen, Yu-Xiao Wei, Jing-Min Zhang, Xiu-Mei Sang, Chuan-Chao Dai*. Transcriptomics analysis investigates sesquiterpenoids accumulation pattern in different tissues of Atractylodes lancea (Thunb.) DC. plantlet. Plant Cell, Tissue and Organ Culture, 2017, 130:73–90.
(17) Fei Chen#, Cheng-Gang Ren#, Tong Zhou, Yu-Jia Wei, Chuan-Chao Dai*. A novel exopolysaccharide elicitor from endophytic fungus Gilmaniella sp. AL12 on volatile oils accumulation in Atractylodes lancea. Scientific Reports, 2016, 6, 34735.
(18) Hai-Long Liu*, Jun-Yong Dai, Jia-Hong Zhou, He-Yong Huang, Fei Chen, Zi-Lie Liu. A hybrid ionic liquid-matrix material, [TiO2-Si-NH3+] [CHC−], as a novel matrix for the analysis of small molecules by MALDI-TOF MS. International Journal of Mass Spectrometry, 2015, 376:85–89.
(19) Fei Chen, Xiao-Hai Feng, Jin-Feng Liang, Hong Xu*, Ping-Kai Ouyang. An oxidoreduction potential shift control strategy for high purity propionic acid production by Propionibacterium freudenreichii CCTCC M207015 with glycerol as sole carbon source. Bioprocess and Biosystems Engineering, 2013, 36(9):1165–1176.
(20) Fei Chen, Xiao-Hai Feng, Hong Xu*, Dan Zhang, Ping-Kai Ouyang. Propionic acid production in a plant fibrous-bed bioreactor with immobilized Propionibacterium freudenreichii CCTCC M207015. Journal of Biotechnology, 2012, 164(2):202–210.
(21) Dan Zhang, Xiao-Hai Feng, Sha Li, Fei Chen, Hong Xu*. Effects of oxygen vectors on the synthesis and molecular weight of poly (γ-glutamic acid) and the metabolic characterization of Bacillus subtilis NX-2. Process Biochemistry, 2012, 47(12):2103–2109.
(22) Xiao-Hai Feng#, Fei Chen#, Hong Xu*, Bo Wu, Hui Li, Sha Li, Ping-Kai Ouyang. Green and economical production of propionic acid by Propionibacterium freudenreichii CCTCC M207015 in plant fibrous-bed bioreactor. Bioresource Technology, 2011, 102(10):6141–6146.
(23) Xiao-Hai Feng, Fei Chen, Hong Xu*, Bo Wu, Jun Yao, Han-Jie Ying, Ping-Kai Ouyang. Propionic acid fermentation by Propionibacterium freudenreichii CCTCC M207015 in a multi-point fibrous-bed bioreactor. Bioprocess and Biosystems Engineering, 2010, 33(9):1077–1085.
(24) 赵萍, 陈飞*, 周家宏. 花生制品中金黄色葡萄球菌SYBR Green qPCR快检方法的评价研究. 南京师范大学学报(工程技术版), 2023, 23(2):69–76.
(25) 赵萍, 张盈月, 周家宏, 陈飞*. 响应面法优化花生中黄曲霉毒素的提取及其在快检评价中的应用. 南京师范大学学报(工程技术版), 2022, 22(3):72–82.
(26) 曹令森, 陈飞, 戴传超*. 茅苍术与内生菌互作信号对其活性成分的影响. 农业环境科学学报, 2022, 41(12):2831–2839.
(27) 田林双, 顾鹏程, 吴存兵, 徐澳, 豆雪梅, 史凤珍, 陈飞*. 小麦粉及其制品中偶氮甲酰胺检测方法研究进展. 食品科学, 2021, 42(9):347–354. (EI)
(28) 刘连红, 陈飞, 管永祥, 仇美华, 张丽, 戴传超*. 枫香拟茎点霉B3生物转化花生废弃物合成白藜芦醇. 食品科学, 2020, 41(6):170–178. (EI)
(29) 陈飘雪, 陈飞, 袁洁, 阳湖荣, 王翟, 郝爱月, 戴传超*. 内生菌复合接种对茅苍术生长和倍半萜积累的影响. 生态学杂志, 2020, 39(9):2944–2952.
(30) 刘连红, 陈飞, 张丽, 仇美华, 管永祥, 戴传超*. 花生的药用成分及其提取分离技术的研究进展. 生物加工过程, 2018, 16(4):40–48.
(31) 陈飞, 周彤, 魏宇佳, 杨晶, 戴传超*. 茅苍术质膜蛋白的制备及其双向电泳蛋白质组学平台的构建. 生物技术通报, 2016, 32(9):72–82.
(32) 陈飞, 李蕾, 周佳宇, 戴传超*. 茅苍术挥发油及主要组分对3种病原菌和2种内生菌的抑菌活性. 江苏农业学报, 2015, 31(6):1270–1277.
(33) 陈飞, 冯小海, 吴波, 李莎, 徐虹*. 丙酸杆菌的两种固定化细胞反应器发酵生产丙酸及其代谢通量分析. 化工学报, 2011, 62(4):1034–1041. (EI)
(34) 陈飞, 张力, 冯小海, 吴波, 徐虹*. 低成本绿色循环工艺发酵生产丙酸联产维生素B12. 生物加工过程, 2011, 9(6):15–20.
(35) 陈飞, 徐虹, 冯小海*, 吴波, 李莎. 外置式植物纤维床反应器与膜分离联用的丙酸发酵工艺研究. 高校化学工程学报, 2010, 24(6):1000–1004. (EI)
l 知识产权：
(1) 江苏省地方标准：茅苍术工厂化育苗技术规程. DB32/T 5074–2025.
(2) 发明专利：粘质沙雷氏菌RZ 21-C6及其应用. ZL2016105939640. (授权)
(3) 发明专利：CYP71P2酶、生物材料及应用. ZL2025100689370. (授权)
(4) 发明专利：一种复合微生物菌剂及其制备方法和应用. CN2024116246289.
(5) 发明专利：一种钩状木霉及其在防治苍术根腐病中的应用. CN2025115755017.
(6) 软件著作权：基于大数据分析的育苗实时监控系统. 2023SR0954419.
(7) 软件著作权：天然活性分子提取检测系统. 2023SR0956125.
(8) 软件著作权：药用植物生态种植监测系统. 2024SR2077996.
l 科技获奖：
(1) 江苏省高校自然科学研究成果奖一等奖：内生菌促进茅苍术活性成分倍半萜积累的机制研究. 苏教人[2018]10号 (第三完成人), 201808.
(2) 江苏省分析测试协会科学技术奖二等奖：非损伤微测技术在“植物-微生物互作离子分子组学”研究上的创新应用. 2024-FXCSJ-E7 (第二完成人), 202412.
l 联系方式：
邮箱：chenfei@njnu.edu.cn; fchennjnu@vip.163.com
地址：南京市栖霞区文苑路1号南京师范大学北区生科院南611室，210023
