戴亦军，男，博士，教授，博士生导师，生命科学学院副院长。
主要研究方向为微生物生物技术，目前从事微生物资源生物技术和微生物降解有机污染物研究，研究内容涉及功能微生物的筛选和鉴定、污染物降解途径分析、代谢酶的基因克隆表达、酶学特性及转录调控机制。主持了4项国家自然科学基金面上项目、环保公益性行业专项等课题；发表SCI论文40余篇，获授权中国发明专利8项。
在教育教学方面，担任国家级线上一流本科课程“微生物学模块化实验”主持人，微生物学实验课校级教学团队主持人。为本科生讲授发酵工程、微生物学实验和生命科学导论等课程，获第三届长三角师范生教学基本功大赛优秀指导教师奖、南京师范大学优秀教学成果一等奖、本科教学奖一等奖。
一、主要科研项目
低营养诱导粘着箭菌啶虫脒腈水合酶基因pnhA表达的转录调控机制研究，国家自然科学基金面上项目, 2020.01-2023.12
细菌代谢吡虫啉的羟基化和硝基还原途径中的关键酶和调节机制研究, 国家自然科学基金面上项目, 2016.01-2019.12
微生物共代谢降解烟碱类杀虫剂吡虫啉的关键酶及其调控机制研究，国家自然科学基金面上项目，2014.01-2014.12
不同共代谢基质控制嗜麦芽寡养单胞菌的吡虫啉代谢途径的机理研究，国家自然科学基金面上项目，2010.01-2012.12
二、发表论文(*,corresponding author)：
(一)主要研究论文
Jiang HY, Yuan PP, Ding JJ, Wu HK, Wang L, Chen KX,Jiang ND, Dai YJ*. Novel biodegradation pathway of insecticide flonicamid mediated by anamidase and its unusual substrate spectrum.Journal of Hazardous Materials, 2023, 441: 129952
Jiang HY, Li HX, Wang YH, Yu XX, Chen XY, Dai YJ*. Biodegradation of the nitrile-containing insecticides sulfoxaflor,flonicamid, thiacloprid, and acetamiprid by immobilized Escherichia coliharboring genes of nitrile hydratase and a cobalt transporter.Journal of Environmental Chemical Engineering, 2023, 11: 109521
JiangHY, Wu HK, Yuan PP, Guo JJ, Wang Li, Dai YJ*.Biodegradation of sulfoxaflor by Pseudomonas stutzeri CGMCC 22915 and characterization of the nitrile hydratase involved. International Biodeterioration & Biodegradation,2022, 170: 105403
Jiang HY, Jiang ND, Wang L, Guo JJ, Chen KX, Dai YJ*. Characterization of nitrilases from Variovorax boronicumulans that functions in insecticide flonicamid degradation and β‐cyano‐L‐alanine detoxification. Journal of Applied Microbiology, 2022, 133(2): 311-322
Cheng X, Chen KX, Jiang ND, Wang L, Jiang HY, Zhao YX, Dai ZL, Dai YJ*.Nitroreduction of imidacloprid by the actinomyceteGordoniaalkanivorans and the stability and acute toxicity of the nitroso metabolite. Chemosphere, 2022, 291:132885
Dai ZL, Yang WL, Fan ZX, Guo L, Liu ZH*, Dai YJ*.Actinomycetes Rhodococcus ruber CGMCC 17550 degrades neonicotinoid insecticide nitenpyram via a novel hydroxylation pathway and remediates nitenpyram in surface water. Chemosphere, 2021, 270:128670
ZhaoYX, GuoL, WangL, JiangND, ChenKX, DaiYJ*.Biodegradation of the pyridinecarboxamide insecticide flonicamid by Microvirga flocculans and characterization of two novel amidases involved. Ecotoxicology and Environmental Safety,2021, 220, 112384
SunSL*, Zhou JS, Jiang JH, Dai YJ*, Sheng MM. Nitrile hydratases: from industrial application to acetamiprid and thiacloprid degradation. Journal of Agricultural and Food Chemistry, 2021,69(36): 10440−10449
Zhao YX, Wang L, Chen KX, Jiang ND, Sun SL, Ge F*, Dai YJ*.Biodegradation of flonicamid by Ensifer adhaerens CGMCC 6315 and enzymaticcharacterization of the nitrile hydratasesinvolved. Microbial Cell Factories, 2021, 20:133
Sun SL, Fan ZX, Zhao J, Dai ZL, Zhao YX, Dai YJ*.Copper stimulates neonicotinoid insecticide thiacloprid degradation by Ensifer adhaerens TMX-23. Journal of Applied Microbiology, 2021, 131 (6): 2838-2848
GuoLL, Yang WL, Cheng X, Fan ZX, Chen XM,Ge F*, Dai YJ*.Degradation of neonicotinoid insecticide acetamiprid by two different nitrile hydratases of Pseudaminobacter salicylatoxidans CGMCC1.17248. International Biodeterioration & Biodegradation, 2021, 157: 105141
YangWL, DaiZL, Cheng X, Fan ZX, JiangHY, DaiYJ*. Biotransformation of insecticide flonicamid by Aminobacter sp. CGMCC 1.17253 via nitrile hydratase catalyzed hydration pathway. Journal of Applied Microbiology, 2021, 130(5): 1571-1581
Yang WL, Fan ZX, Jiang HY, Zhao YX, Guo L, Dai YJ*.Biotransformation of flonicamid and sulfoxaflor by multifunctional bacterium Ensifer meliloti CGMCC 7333. Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes,2021, 56(2): 122-131
Zhao YX, Yang WL, Guo L, Jiang HY, Cheng X, Dai YJ*.Bioinformatics of a novel nitrile hydratase gene cluster of the N2-fixing bacterium Microvirga flocculans CGMCC 1.16731 and characterization of the enzyme.Journal of Agricultural and Food Chemistry,2020, 68(35): 9299-9307
Guo L, Cheng X, Jiang HY, Dai YJ*. Maturation mechanism of nitrile hydratase from Streptomyces canus CGMCC 13662 and its structural character. Frontiers in Microbiology, 2020, 11: 1419
Yang WL, Dai ZL, Guo L, Fan ZX, Ge F*, Dai YJ*. Sulfoxaflor degraded by Aminobacter sp. CGMCC 1.17253 through hydration pathway mediated by nitrile hydratase. Journal of Agricultural and Food Chemistry,2020, 68(16): 4579-4587
Wang YX, Wang G, Dai YJ*, Wang Y, Lee YW, Shi JR* and Xu JH*. Biodegradation of deoxynivalenol by a novel microbial consortium. Frontiers in Microbiology, 2020, 10: 2964
Guo LL, Dai ZL, Guo JJ, Yang WL, Ge F*, Dai YJ*. Oligotrophic bacterium Hymenobacterlatericoloratus CGMCC 16346 degrades the neonicotinoid imidacloprid in surface water, AMB Express, 2020, 10: 7
Zhao YX, Guo LL, Sun SL, Guo JJ, Dai YJ*. Bioconversion of indole-3-acetonitrile by the N2-fixing bacterium Ensifer meliloti CGMCC 7333 and its Escherichia coli-expressed nitrile hydratase. International Microbiology, 2020, 23(2): 225–232
Yang WL, Guo LL, Dai ZL, Qin RC, Zhao YX, and Dai YJ*. Biodegradation of the insecticide flonicamid by Alcaligenes faecalis CGMCC 17553 via hydrolysis and hydration pathways mediated by nitrilase. Journal of Agricultural and Food Chemistry,2019, 67(36): 10032−10041
Guo L, Fang WW, Guo LL, Yao CF, Zhao YX, Ge F*, Dai YJ*. Biodegradation of the neonicotinoid insecticide acetamiprid by actinomycetes Streptomyces canus CGMCC 13662 and characterization of the novel nitrile hydratase involved. Journal of Agricultural and Food Chemistry,2019, 67(21): 5922-5931
Sun SL, Fan ZX, Zhao YX, Guo LL, Dai YJ* (2019) A novel nutrient deprivation-induced neonicotinoid insecticide acetamiprid degradation by Ensifer adhaerens CGMCC 6315. Journal of Agricultural and Food Chemistry,67(1): 63-71
Zhao YX, Jiang HY, Chen X, Zhu YX, Fan ZX, Dai ZL, Guo L, Liu ZH*, Dai YJ*. Neonicotinoid thiacloprid transformation by the N2-fixing bacterium Microvirga flocculans CGMCC 1.16731 and toxicity of the amide metabolite. International Biodeterioration & Biodegradation,2019, 145(11): 104806
郭静静, 郭磊磊, 赵云岫, 戴亦军*. Ensifer meliloti 1021烟酰胺酶的酶学特性及3-氰基吡啶调控机理的研究, 生物技术通报, 2019, 35(8): 51-58
郭静静, 郭磊磊, 赵云岫, 葛峰*, 戴亦军*; 固氮菌Ensifer meliloti 1021降解苯甲腈及其代谢酶的基因克隆和表达, 生态与农村环境学报, 2019, 35(2): 248-254
Sun SL, Yang WL, Fang WW, Zhao YX, Guo L, Dai YJ*. The plant growthpromoting rhizobacterium Variovorax boronicumulans CGMCC 4969 regulates the level of indole-3-acetic acid synthesized from indole-3-acetonitrile. Applied and Environmental Microbiology,2018, 84(16): e00298-18
Sun SL, Yang WL, Guo JJ, Zhou YN, Rui X, Chen C, Ge F*, Dai YJ*. Biodegradation of the neonicotinoid insecticide acetamiprid in surface water by the bacterium Variovorax boronicumulans CGMCC 4969 and its enzymatic mechanism. RSC Advances, 2017,7(41): 25387–25397
Lu TQ, Mao SY, Sun SL, Yang WL, Ge F*, Dai YJ*.Regulation of hydroxylation and nitroreductionpathways during metabolism of the neonicotinoid insecticide imidacloprid byPseudomonas putida. Journal of Agricultural and Food Chemistry,2016, 64(24): 4866–4875
Sun SL, Lu TQ, Yang WL, Guo JJ, Rui X, Mao SY, Zhou LY, Dai YJ*.Characterization of a versatile nitrile hydratase of the neonicotinoid thiacloprid-degrading bacterium Ensifer meliloti CGMCC 7333.RSC Advances,2016, 6(19): 15501–15508
Zhou LY, Zhang LJ*, Sun SL, Ge F, Mao SY, Ma Y, Liu ZH, Dai YJ*, Yuan S.Degradation of the neonicotinoid insecticide acetamiprid via the N-carbamoyliminederivate (IM-1-2) mediated by the nitrile hydratase of the nitrogen-fixing bacterium Ensifer meliloti CGMCC 7333. Journal of Agricultural and Food Chemistry,2014, 62(41): 9957-9964
Ge F, Zhou LY, Wang Y, Ma Y, Zhai S, Liu ZH, Dai YJ*, Yuan S.Hydrolysis of the neonicotinoid insecticide thiacloprid by the N2-fixing bacterium Ensifer meliloti CGMCC 7333. International Biodeterioration & Biodegradation,2014, 93:10-17
Ma Y, Zhai S, Mao SY, Sun SL, Wang Y, Liu ZH, Dai YJ*, Yuan S.Co-metabolic transformation of the neonicotinoid insecticide imidacloprid by the new soil isolate Pseudoxanthomonas indicaCGMCC 6648. Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes,2014, 49(9): 661-670
Zhou GC, Wang Y, Ma Y, Zhai S, Zhou LY, Dai YJ*, Yuan S. The metabolism of neonicotinoid insecticide thiamethoxam by soil enrichment cultures, and the bacterial diversity and plant growth promoting properties of the cultured isolates.Journal of Environmental Science and Health, Part B: Pesticides, Food Contaminants, and Agricultural Wastes, 2014, 49(6): 381-390
Zhou GC, Wang Y, Zhai S, Ge F, Liu ZH, Dai YJ*, Yuan S, Hou JY.Biodegradation of the neonicotinoid insecticide thiamethoxam by the nitrogen-fixing and plant-growth-promoting rhizobacterium Ensiferadhaerens strain TMX-23. Applied Microbiology and Biotechnology,2013, 97(9): 4065–4074
Liu ZH, Cao YM, Zhou QW, Guo K, Ge F*, Hou JY, Hu SY, Yuan S, Dai YJ*. Acrylamide biodegradation ability and plant growth-promoting properties of Variovorax boronicumulans CGMCC 4969. Biodegradation,2013, 24:855–864
Liu ZH, Dai YJ*, Huan Y, Liu ZX, Sun Lei, Zhou QW, Zhang WJ, Sang Q, Wei H, Yuan S*. Different utilizable substrates have different effects on cometabolic fate of imidacloprid in Stenotrophomonas maltophilia. Applied Microbiology and Biotechnology,2013, 97:6537–6547
Liu ZH, Cao YM, Dai YJ, Ni JP, Wei H, Yuan S*. Pretreatment with Stenotrophomonas maltophilia CGMCC 1.1788 increased the aphicidal activity of imidacloprid. Journal of Pesticide Science, 2013,38(3): 139–143
Zhang HJ, Zhou QW, Zhou GC, Cao YM,Dai YJ*, Ji WW, Shang GD, Yuan S*. Biotransformation of the neonicotinoid insecticide thiacloprid by bacterium Variovorax boronicumulans strain J1 and mediation of the major metabolic pathway by nitrile hydratase. Journal of Agricultural and Food Chemistry, 2012,60(1):153–159
Liu ZH, Dai YJ*, Huang GD, Gu YY, Ni JP, Wei H, Yuan S*. Soil microbial degradation of neonicotinoid insecticides imidacloprid, acetamiprid, thiacloprid and imidaclothiz and its effect on the persistence of bioefficacy against horsebean aphid Aphis craccivora Koch after soil application. Pest Management Science, 2011, 67(10):1245-1252
Dai YJ, Zhao YJ, Zhang WJ, Yu CG, Ji WW, Xu WP, Ni JP, Yuan S*. Biotransformation of thianicotinyl neonicotinoid insecticides: Diverse molecular substituents response to metabolism by bacterium Stenotrophomonas maltophilia CGMCC 1.1788. Bioresource Technology, 2010,101:3838-3843
Dai YJ, Ji WW, Chen T, Zhang WJ, Liu ZH, Ge F, Yuan S*. Metabolism of the neonicotinoid insecticides acetamiprid and thiacloprid by the yeast Rhodotorulamucilaginosa Strain IM-2. Journal of Agricultural and Food Chemistry,2010, 58:2419–2425
Zhao YJ, Dai YJ, Yu CG, Luo J, Xu WP, Ni JP Yuan S*. Hydroxylation of thiacloprid by bacterium Stenotrophomonas maltophilia CGMCC1.1788. Biodegradation,2009, 20: 761-768
Chen T, Dai YJ (co-first author), Ding JF, Yuan S*, Ni JP.N-demethylation of neonicotinoid insecticide acetamiprid by bacterium Stenotrophomonas maltophilia CGMCC 1.1788. Biodegradation, 2008,19:651-658
Dai YJ, Chen T, Ge F, Huan Y, Yuan S*, Zhu FF. Enhanced hydroxylation of imidacloprid by Stenotrophomonas maltophilia upon addition of sucrose. Applied Microbiology and Biotechnology,2007, 74:995-1000
Dai YJ, Yuan S*, Ge F, Chen T, Xu SC, Ni JP. Microbial hydroxylation of imidacloprid for synthesis of highly insecticidal olefin imidacloprid. Applied Microbiology and Biotechnology, 2006, 71:927-934
(二)教改论文
戴亦军, 何伟, 刘中华, 贾永, 袁生, 戴传超*. 一流课程“微生物学模块化实验”的建设与实践. 微生物学通报, 2022,49(4): 1334-1342
何伟, 刘中华, 贾永, 张石柱, 韩管助, 许凯, 戴亦军*, 袁生. 综合性、研究型微生物学实验课的过程性考核. 微生物学通报,2020, 47(4): 1218−1223
戴亦军, 何伟, 袁生*, 刘中华, 贾永,韩管助. “互联网+”背景下微生物学实验课程的改革与实践. 微生物学通报, 2018, 45(3): 683−690 (荣获2018年度微生物学通报优秀论文奖)
魏华,梅艳珍,戴亦军*,袁生.生物发酵制品实训课程教学模式探讨.酿酒, 2018, 45(2): 11-15
戴亦军, 何伟, 袁生*, 刘中华, 贾永, 张石柱. 研究型模块实验“产淀粉酶菌株的筛选、发酵条件优化、菌种鉴定和选育”的教学实践. 微生物学通报, 2017,44(4):976-982
戴亦军, 何伟, 袁生*, 徐旭士, 戴传超. 水质微生物学检验实验模块的教学探索与实践. 微生物学通报, 2016, 43(1): 211−216
梅艳珍，魏华，戴亦军*，戴传超，袁生.建设啤酒生产实训课程,提高理科高校本科生综合实践能力.大学教育, 2016, 59(11):136-139
戴亦军, 何伟, 袁生*, 徐旭士, 贾永, 刘中华, 张石柱, 梅艳珍. 模块化微生物学实验课教学体系的探索与实践. 微生物学通报, 2015, 42(9): 1809−1816
戴亦军, 徐旭士, 袁生, 何伟, 贾永, 梅艳珍, 张石柱, 刘中华. 新课标视角下的高师微生物实验课程探究性教学研究. 大学教育, 2015, 58 (4): 139−141
通讯地址：南京市文苑路1号，南京师范大学生命科学学院，邮编：210023，Email: daiyijun@njnu.edu.cn
