马飞、博士、教授、博士生导师。主要从事动物分子免疫与生物信息学研究。兼任中国昆虫学会昆虫生理生化与分子生物学专委会委员、江苏省动物学会理事、江苏省生物医学工程学会生物信息学专业委员会委员、美国遗传学会会员。2007年入选教育部新世纪优秀人才、2010年入选南京师范大学青蓝工程中青年学术带头人、2011年度荣获南京师范大学“优秀教师奖”。已主持国家自然科学基金、教育部“新世纪优秀人才支持计划”、863计划专题以及国家转基因生物新品种培育重大科技专项子课题10余项。已申请国家发明专利1项。在国内外重要学术刊物上发表论文100余篇。参编学术著作和教材3部、获省部级自然科学和科技进步奖各1项。

研究方向

1.非编码RNA在昆虫免疫与发育中的调控机制研究；

2.生物大数据分析与网络生物学研究。

出版的著作

1.程遐年，吴进才，马飞编著.《褐飞虱的研究与防治》.北京：中国农业出版社. 2003年（本书获2002年国家科学技术学术著作出版基金的专项出版资助）。

2.肖浪涛，主编，马飞参编.十一五《生物信息学》教材.北京：中国农业出版社. 2006年。

3.李庆伟，马飞编著.《鸟类分子进化与分子系统学》.北京：科学出版社. 2007年。

近五年发表的主要论文：

昆虫分子免疫与发育生物学研究

1.Yao X, Ni J, Lin L, Jin P, Ma F. The NF-κB/Relish Activates miR-308 to Negatively Regulate Imd Pathway Immune Signaling inDrosophila.The Journal of Immunology,2023; ji2200680.https://doi.org/10.4049/jimmunol.2200680.

2.Li H, Yu Z, Niu Z, Cheng Y, Wei Z, Cai Y,Ma F, Hu L, Zhu J, Zhang W.A neuroprotective role of Ufmylation through Atg9 in the aging brain ofDrosophila.Cellular and Molecular Life Sciences, 2023, 80(5): 129.

3.ZhouH, WuS, LiuL, LiuX, LanS, JiangJ, YangW,JinP, XiaX,MaF.DrosophilaRelish-mediated miR-317 expression facilitates immune homeostasis restoration via inhibiting PGRP-LC.European Journal of Immunology, 2022, 52(12):1934-1945.

4.Zhou H, Li S, Pan W, Wu S,Ma F, Jin P.Interaction of lncRNA-CR33942 with Dif/Dorsal Facilitates Antimicrobial Peptide Transcriptions and EnhancesDrosophilaToll Immune Responses.The Journal of Immunology, 2022, 208(8): 1978-1988.

5.Li R, Yao X, Zhou H, Jin P,Ma F. TheDrosophilamiR-959–962 Cluster Members Repress Toll Signaling to Regulate Antibacterial Defense during Bacterial Infection.International Journal of Molecular Sciences, 2021, 22: 886.

6.LiR, ZhouH, JiaC, JinP,MaF.DrosophilaMyc restores immune homeostasis of Imd pathway via activating miR-277 to inhibit imd/Tab2.PLOS Genetics, 2020, 16(8):e1008989.

7.Zhou X, Hu, Fu M, Jin P, Zhang Y, Xiang Y, Li Y,Ma F.Identification and characterization of a TLR13 gene homologue from Laodelphax striatellus involved in the immune response induced by rice stripe virus.Journal of Integrative Agriculture, 2020, 19(1): 183-192.

8.WeiG, SunL, QinS, LiR, ChenL, JinP,MaF. Dme-Hsa Disease Database (DHDD): Conserved Human Disease-Related miRNA and Their Targeting Genes inDrosophila melanogaster.International Journal of Molecular Sciences, 2018, 19(9):2642.

9.Li S,Li Y,Shen L,Jin P,Chen L,Ma F. miR-958 inhibits Toll signaling andDrosomycinexpression via directly targeting Toll and Dif inDrosophila melanogaster.Am J Physiol-Cell Physiol., 2017, 312(2):C103-C110.

10.Li Y, Li S, Jin P, Chen L,Ma F.miR-11 regulates pupal size ofDrosophila melanogastervia directly targeting Ras85D.Am J Physiol-Cell Physiol., 2017, 312(1): C71-C82.

生物信息与网路生物学研究

1.Guan M, Cao Y, Wang X, Xu X, Ning C, Qian J,Ma F, Zhang X. Characterizing temporal variability and repeatability of dose-dependent functional genomics approach for evaluating triclosan toxification,Science of The Total Environment, 2023, 165209, https://doi.org/10.1016/j.scitotenv.2023.165209.

2.Guan M, Wang X, Pan Y, Xu Y, Cao Y, Yan L, Ma L,Ma F, Zhang X.Delving into the molecular initiating event of cadmium toxification via the dose-dependent functional genomics approach in Saccharomyces cerevisiae.Environmental Pollution, 2023, 323: 121287.

3.Huang L, Qin S, Xia L,Ma F, Chen .Integrative single-cell sequencing analysis distinguishes survival-associated cells from the breast cancer microenvironment.Cancer Medicine, 2023, 12(11):12896-12911.

4.Ma X, Zhang S, Qin S, Guo J, Yuan J, Qiang R, Zhou S, Cao W, Yang J,Ma F,Chai R.Transcriptomic and epigenomic analyses explore the potential role of H3K4me3 in neomycin-induced cochlear Lgr5+progenitor cell regeneration of hair cells.Human Cell, 2022, 35(4): 1030-1044.

5.Wang C, Qin S, Pan W, Shi X, Gao H, Jin P, Xia X,Ma F. mRNAsi-related genes can effectively distinguish hepatocellular carcinoma into new molecular subtypes.Computational and Structural Biotechnology Journal, 2022, 20:2928-2941.

6.Guan M, Yan L, Li R, Xu Y, Chen D, Li S,Ma F, Zhang X.Integration of leave-one-out method and real-time live cell reporter array system to assess the toxicity of mixtures.Environmental Research, 2022, 214: 114110.

7.Qin S, Xu W, Wang C, Jiang S, Dai W, Yang Y, Shen J, Jin P,Ma F, Xia X.Analyzing master regulators and scRNA-seq of COVID-19 patients reveals an underlying anti-SARS-CoV-2 mechanism of ZNF proteins.Briefings in Bioinformatics, 2021, 22(5): bbab118.

8.Qin S, Xu J, Yi Y, Jiang S, Jin P, Xia X,Ma F. Transcription Factors and Methylation Drive Prognostic miRNA Dysregulation in Hepatocellular Carcinoma.Frontiers in Oncology, 2021, 11:691115.

9.QinS, XiaX, ShiX, Ji X,MaF,ChenL. Mechanistic insights into SARS-CoV-2 epidemic via revealing the features of SARS-CoV-2 coding proteins and host responses upon its infection.Bioinformatics, 2020, 36(21):5133-5138.

10.QinS, ShiX, WangC, JinP,MaF.Transcription Factor and miRNA Interplays Can Manifest the Survival of ccRCC Patients.Cancers(Basel)，2019, 11(11):1668.

个人实验室网址：http://bioinf.njnu.edu.cn/

联系方式：南京市仙林文苑路1号南京师范大学生命科学院（210046）

E-mail:mafei01@tsinghua.org.cn或mafei @njnu.edu.cn