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学术预告:“Lipid droplet metabolism”

应江苏省分子医学生物技术重点实验室胡志刚副教授的邀请,美国斯坦福大学研究员 Wen-Jun Shen博士来我校进行学术交流并作报告。

报告题目:“Lipid droplet metabolism”,
报告人:Dr. Wen-Jun Shen  美国斯坦福大学医学院
时间:2015年1月29日(星期四) 上午10:00
地点:生科院3楼圆形会议室

Wen-Jun Shen博士简介:
教育经历:
1986-1988  中国农业大学 本科
1988-1991  英国伦敦大学  博士
工作经历:
1991-1993   Postdoctoral Fellow, University College, London, UK
1993-1996   Postdoctoral Fellow, Baylor College of Medicine, Houston, TX
1996-2001   Research Associate, Stanford University
2001-present   Senior Research Scientist, Stanford University

代表性论文:

Shen W-J, Patel S, Miyoshi H, Greenberg AS, Kraemer FB. Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res. 2009 Nov;50(11) :2306-2313.
Shen W-J, Patel S, Eriksson JE, Kraemer FB. Vimentin is a functional partner of hormone sensitive lipase and facilitates lipolysis. J Proteome Res. 2010 Apr 5;9(4): 1786-1794
Shen W-J, Yu Z, Patel S, Jue D, Liu LF, Kraemer FB.  Hormone-sensitive lipase modulates adipose metabolism through PPARg.   Biochim Biophys Acta. (2011)1811(1):9-16.
Shen W-J,  Zaidi SF,  Patel S, Cortez Y,  Ueno M, Azhar R, Azhar S, and  Kraemer FB, Ablation of Vimentin Result in Defective Steroidogenesis. Endocrinology. 2012 Jul;153(7):3249-57
Hu Z, Shen W-J, Kraemer FB, Azhar S. MicroRNAs 125a and 455 repress lipoprotein-supported steroidogenesis by targeting scavenger receptor class B type I in steroidogenic cells.  Mol Cell Biol. 2012 Dec;32(24):5035-45.
Liu LF, Shen W-J, Ueno M, Patel S, Azhar S, Kraemer FB. Age-related modulation of the effects of obesity on gene expression profiles of mouse bone marrow and epididymal adipocytes. PLoS One. 2013 Aug 14;8(8):e72367. doi: 10.1371/journal.pone.0072367.
Khor VK, Shen W-J, Kraemer FB. Lipid droplet metabolism. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):632-7.
Zaidi SK, Shen W-J, Bittner S, Bittner A, McLean MP, Han J, Davis RJ, Kraemer FB, Azhar S. p38  MAPK regulates steroidogenesis through transcriptional repression of StAR gene. J Mol Endocrinol. 2014 Apr 29. [Epub ahead of print].
Shen W-J, Hu J, Hu Z, Kraemer FB, Azhar S. Scavenger receptor class B type I (SR-BI): A versatile receptor with multiple functions and actions. Metabolism. 2014 Jul;63(7):875-886. doi: 10.1016/j.metabol.2014.03.011. Epub 2014 Mar 21.

欢迎大家参加!