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刘莉*

  • 基本情况

刘莉,研究员,医学博士学位,发育生物学系硕士研究生导师,江苏省“333工程高层次人才培养工程中青年科学技术带头人,就职于南京医科大学一附院/江苏省人民医院老年医学科。获得20192007年度江苏省科技进步二等奖。

通讯地址:南京市广州路300号,江苏省人民医院老年医学科A2楼,邮编210029

Email: liuli@njmu.edu.cn

电话:025-68305021(办公室)13951852880(手机)

 

  • 研究方向
    1. 心肌损伤的分子机制及干预
    2. 代谢综合征的发病机制及干预

 

  • 在研项目
  1. 国家自然科学基金 (编号: 81970692):巨噬细胞HSPA12A基因沉默对II型糖尿病的保护作用及机制研究
  2. 国家自然科学基金 (编号: 81770854)HSPA12A基因沉默对非酒精性脂肪肝病的保护作用及机制研究

 

  • 3年发表的主要论著
  1. Liu J, Du S, Kong Q, Zhang X, Jiang S, Cao X, Li Y, Li C, Chen H, Ding Z, Liu L*. HSPA12A attenuates lipopolysaccharide-induced liver injury through inhibiting caspase-11-mediated hepatocyte pyroptosis via PGC-1α-dependent acyloxyacyl hydrolase expression. Cell death & differentiation 2020;27(9):2651-2667. (IF: 10.717)
  2.  Zhang X#, Chen X#, Qi T, Kong Q, Cheng H, Cao X, Li Y, Li C, Liu L*, Ding Z*. HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ. Cell death & differentiation 2019;26(11):2253-2267. (IF: 10.717)
  3. Kong Q, Li N, Cheng H, Zhang X, Cao X, Qi T, Dai L, Zhang Z, Chen X, Li C, Li Y, Xue B, Fang L, Liu L*, Ding Z*. HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. Diabetes 2019;68(2):361-376. (IF: 7.720)
  4. Wang Y#, Liu J#, Kong Q, Cheng H, Tu F, Yu P, Liu Y, Zhang X, Li C, Li Y, Min X, Du S, Ding Z, Liu L*. Cardiomyocyte-specific deficiency of HSPB1 worsens cardiac dysfunction by activating NFκB-mediated leucocyte recruitment after myocardial infarction. Cardiovascular research 2019;115(1):154-167. (IF: 8.168)
  5. Zhao Y, Liu C, Liu J, Kong Q, Mao Y, Cheng H, Li N, Zhang X, Li C, Li Y, Liu L*, Ding Z*. HSPA12B promotes functional recovery after ischaemic stroke through an eNOS-dependent mechanism. Journal of cellular and molecular medicine 2018;22(4):2252-2262. (IF: 4.486)