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刘贵友*

博士、教授、硕士生导师

通讯地址:南京市石湫街道新河西路6号,邮编:211200

Email: lgy@jssnu.edu.cn

 

基本情况:

男,19738月生,江苏南京人。

2003年毕业于南京师范大学细胞生物学专业,获理学硕士学位;2013年毕业于南京师范大学微生物学专业,获理学博士学位。现为江苏第二师范学院党委常委、副院长,主要从事微生物学教学和科研工作。

   

    研究方向:

    1. 微生物代谢调控

    2. 微生物药物合成

 

    主持研究项目

    1. 江苏省自然科学基金项目《朊病毒蛋白基因PRNP调控脂肪细胞分化的作用与机制》(BK20151466

    2. 江苏省高校自然科学研究重大项目《球毛壳菌生物转化产生新生物碱农药先导化合物的研究》(19KJA430013

 

   代表性论文:

    1. Lei Sun, Guiyou Liu, Ya Li, Dayong Jiang, Wenfeng Guo, Hui Xu, Ruoting Zhan. Metabolic engineering of Saccharomycescerevisiae for efficient production of endocrocin and emodin, Metabolic Engineering. 2019; 54; 212-221. (共同一作)

    2. Yun Li, Yahui Zhou, Lijun Zhu, Guiyou Liu, Xing Wang, Xingyun Wang, Jian Wang, Lianghui You, Chenbo Ji, Xirong Guo, Yingmin Zhao, Xianwei Cui. Genome-wide analysis reveals that altered methylation in specific CpG loci is associated with childhood obesity, J Cell Biochem. 2018; 119(9):7490-7497.

    3. Guiyou Liu, Zhonghua Liu and Sheng Yuan. Recent Advances in Methods of Puerarin Biotransformation. Mini-Reviews in Medicinal Chemistry, 16(17): 1392-1402.

    4. Guiyou Liu, Lei Sun, Xiuxiu Wu, et al. Immobilization of puerarin glycosidase from Microbacterium oxydans CGMCC 1788 increases puerarin transformation efficiency, Brazilian Journal of Chemical Engineering, 2014, 31(2): 325-333.

    5. Xiao W, Long W, Liu G, et al. Molecular cloning, expression and functional analysis of B-cell activating factor (BAFF) in yellow grouper, Epinephelus awoara. Molecular Immunology, 2014, 59(1): 64-70.

    6. Siyuan Wang, Guiyou Liu*, Wen Zhang, et al. Efficient glycosylation of puerarin by an organic solvent-tolerant strain of Lysinibacillus fusiformis [J], Enzyme and Microbial Technology, 2014, 57: 42-47.

    7. Liu G.Y., Sun L., Wang S.Y., et al. Hydroxylation modification and free radical scavenging activity of puerarin-7-O-fructoside. Folia        Microbiol, 2011, 56(4): 305-311.

    8. Cigang Yu, Haidong Xu, Guodong Huang, Ting Chen, Guiyou Liu, Nan chai, Yin Ji, Siyuan Wang, Yijun Dai, Sheng Yuan, Permeabilization of Microbacterium oxydans shifts the conversion of puerarin from puerarin-7-O-glucoside to puerarin-7-O-fructosideApplied Microbiology and Biotechnology, 2010, 86: 863-870.

    9. Shouchuang Zhu, Haidong Xu, Cigang Yu, Juanfang Ding, Ting Chen, Jierong Jiang, Yijun Dai, Guiyou Liu, Guodong Huang, Nan Chai, Xuhua Jiang and Sheng Yuan, Preparation of a super-long two column chromatography system and its application in separating glycosylated puerarin, Biomedical Chromatography, 2009, 23(13): 1344-1349

    10. Hui Ye, Haidong Xu, Cigang Yu, Yijun Dai, Guiyou Liu, Wenping Xu, Sheng Yuan, Hydroxylation of naringin by Trichoderma harzianum to dramatically improve its antioxidative activity, Enzyme and Microbial Technology, 2009, 45: 282–287

    11. LiuGui-you, Yuan Sheng, DaiChuan-chao. Factors affecting γ-linolenic acid content in fermented glutinous rice brewed by Rhizopus sp, Food Microbioloy, 21 (2004):299-304.