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梁廷明

姓名:梁廷明
职称:副教授 
学位:理学博士
 

学习及工作经历
2016年9月-至今,南京师范大学生命科学学院,副教授
2011年10月-2016年8月,南京师范大学生命科学学院,讲师

2006年9月-2011年6月,南京师范大学,生命科学学院,理学博士

1999年9月-2003年6月,信阳师范学院,生命科学学院,理学学士

 

本科教学:主讲《细胞生物学》、《现代分子生物学》、《细胞生物学实验》

 

研究方向:非编码RNA(包括miRNA和LncRNA)在代谢性疾病和肿瘤中的调控作用。

 

主持的科研项目
1. 国家自然科学基金青年基金项目,2014-2017
2. 江苏省高校自然科学研究面上项目,2012.8-2014.12
3. 南京师范大学高层次人才科研启动基金,2013-2016

4. 江苏省生物学优势学科II期建设项目(青年教师提升计划),2015-2017

 

荣誉和奖励
2016年:南京师范大学“青蓝工程”优秀中青年骨干教师”,2016/01-2018/12

2014年:教育部高等学校科学研究优秀成果奖(科学技术)自然科学奖二等奖(排名第八)

2013年:第二届江苏侨界贡献奖(创新团队)(排名第六)

2013年:第三届江苏省海洋与渔业科技创新奖一等奖(排名第九)

 

主要学术兼职
国际心脏学会中国分会会员;江苏省发育与细胞生物学会会员。

 

发表论文列表:

  1. Guo, L.*, Liang, T.*, microRNAs and their variants in an RNA world: implications for complex interactions and diverse roles in an RNA regulatory network, Brief Bioinform ,2017, doi: 10.1093/bib/bbw124, in press. (Co-Corresponding author)

  2. Guo, L., Zhang, Q., Ma, X., Wang, J., Liang, T.*, miRNA and mRNA expression analysis reveals potential sex-biased miRNA expression. 2017, Sci Rep, 7, 39812. (Corresponding author)

  3. Guo, L., Liang, T., Yu, J., Zou, Q.*, A comprehensive analysis of miRNA/isomiR expression with gender difference, PLoS ONE, 2016, 11(5), e0154955.

  4. Zhang, W., Wang, P., Chen, S., Zhang, Z., Liang, T.,* and Liu, C.,*. Rhythmic expression of miR-27 targets the clock gene bmal1 through post-transcriptional regulation in the mouse liver. 2016, FASEB Journal 30, 2151-2160. (Co-Corresponding author)

  5. Guo, L.*, Yu, J., Liang, T., Zou, Q., miR-isomiRExp: a web-server for the analysis of expression of miRNA at the miRNA/isomiR levels, Sci Rep, 2016, 6, 23700. doi:10.1038/srep23700.

  6. Liang, T., Yu, J., Liu, C., Guo, L.,*. IsomiR expression patterns in Canonical and Dicer-independent miRNAs, 2017, Mol Med Rep, 15:1071-1078.

  7. Liang, T., Yang, C., Li, P., Liu, C. and Guo, L.,*. Genetic analysis of loop sequences in the let-7 gene family reveal a relationship between loop evolution and multiple isomiRs. 2014. PLoS One 9, e113042.

  8. Liang, T., Yu, J., Liu, C. and Guo, L.,*. An exploration of evolution, maturation, expression and function relationships in mir-23 - 27 - 24 cluster. 2014. PLoS One 9, e106223.

  9. Liang, T.,* Liu, C. and Ye, Z., Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. 2013. PLoS One 8, e80774. (Corresponding author)

  10. Liang, T., Guo, L. and Liu, C.,*. Genome-wide analysis of mir-548 gene family reveals evolutionary and functional implications. 2012. J Biomed Biotechnol 2012, 679563.

  11. Liang, T., Ji, H., Du, J., Ou, J., Li, W., Wu, T., Meng, Q., Gu, W. and Wang, W.,*. Primary culture of hemocytes from Eriocheir sinensis and their immune effects to the novel crustacean pathogen Spiroplasma eriocheiris. 2012. Mol Biol Rep 39, 9747-9754. (IF:1.958)

  12. Liang, T., Wu, T., Du, J., Ji, H., Li, Y., Gu, W. and Wang, W., Characterization of a tailless white spot syndrome virus from diseased Penaeus vannamei and Procambarus clarkii in China. 2011. Afr J Biotechnol 10, 13936-13942.

  13. Liang, T., Li, X., Du, J., Yao, W., Sun, G., & Dong, X., et al. Identification and isolation of a spiroplasma pathogen from diseased freshwater prawns, macrobrachium rosenbergii , in china: a new freshwater crustacean host. 2011.Aquaculture, 318, 1, 1–6.

  14. Liang, T., Ji, H., Lian, L., Wu, T., Gu, W., & Wang, W. A rapid assay for simultaneous detection of spiroplasma eriocheiris and white spot syndrome virus in procambarus clarkii by multiplex pcr. 2010. Lett Appl Microbiol, 51, 5, 532–538.

  15. Liang, T., Qi Feng, Ting Wu, Wei Gu, Wen Wang*. Use of oxytetracycline for the treatment of tremor disease in the Chinese mitten crab (Eriocheir sinensis). 2009. Dis Aquat Organ 84:243-250.

  16. Guo, L. #*, Li, H. #, Liang, T. #, Lu, J., Yang, Q., Ge, Q. and Lu, Z.,*. Consistent isomiR expression patterns and 3' addition events in miRNA gene clusters and families implicate functional and evolutionary relationships. 2012. Mol Biol Rep 39, 6699-706.

  17. Ge, X., Chen, S., Liu, M., Liang, T., Liu, C. Evodiamine inhibits pdgf‑bb‑induced proliferation of rat vascular smooth muscle cells through the suppression of cell cycle progression and oxidative stress. (2016). Mol Medicine Rep 14:4551-4558

  18. Ge X, Chen S, Liu M, Liang T, Liu C*, Evodiamine Attenuates PDGF-BB-induced Migration of Rat Vascular Smooth Muscle Cells through Activating PPARγ, 2015. Int J Mol Sci,16(12):28180-28193.

  19. Chen, S., Ding, Y., Tao, W., Zhang, W., Liang, T. and Liu, C.,*. Naringenin inhibits TNF-α induced VSMC proliferation and migration via induction of HO-1. 2012. Food Chem Toxicol. 50, 3025-3031.

  20. Chen, S., Qian, J., Shi, X., Gao, T., Liang, T. and Liu, C.,*. Control of hepatic gluconeogenesis by the promyelocytic leukemia zinc finger protein. 2014. Mol Endocrinol. 28, 1987-1998.

  21. Wang, Z., Zhang, X., Chen, S., Wang, D., Wu, J., Liang, T. and Liu, C.,*. Lithium chloride inhibits vascular smooth muscle cell proliferation and migration and alleviates injury-induced neointimal hyperplasia via induction of PGC-1alpha. 2013. PLoS One 8, e55471.

  22. Yi, N. #, Chen, S. #, Ma, A., Chen, P., Yao, B., Liang, T. and Liu, C.,*. Tunicamycin Inhibits PDGF‐BB‐Induced Proliferation and Migration of Vascular Smooth Muscle Cells Through Induction of HO-1. 2012. The Anatomical Record 295, 1462-1472.

  23. Guo, L., Liang, T., and Lu, Z.,*. A comprehensive study of multiple mapping and feature selection for correction strategy in the analysis of small RNAs from SOLiD sequencing. 2011. Biosystems. 104: 87–93.

  24. Guo, L., Liang, T., Gu, W., Xu, Y., Bai, Y., Lu, Z.,*. 2011. Cross-mapping events in miRNAs reveal potential miRNA-mimics and evolutionary implication. PLoS ONE. 6(5): e20517

  25. Feng, Q., Wu, G., Liang, T., Ji, H., Jiang, X., Gu, W., and Wang, W.,*. Pharmacokinetics of oxytetracycline in hemolymph from the Chinese mitten crab, Eriocheir sinensis. 2011. J. Vet. Pharmacol. Therap. 34, 51–57.

  26. Meng, Q., Li, W., Liang, T., Jiang, X., Gu, W., Wang, W., *. Identification of adhesin-like protein ALP41 from Spiroplasma eriocheiris and induction immune response of Eriocheir sinensis. 2010. Fish Shellfish Immun. 4:578-593.

  27. Feng, Q., Gao, T., Ji, H., Jiang, X., Liang, T., Gu, W., Wu, G., Gao, G., and Wang, W., *. Kinetic analysis of oxytetracycline residues in Chinese mitten crab (Eriocheir sinensis) muscle following intramuscular administration. 2010. J Fish Dis, 8: 639-647.

  28. Wang, J., Huang, H., Feng, Q., Liang, T., Bi, K., Gu, W., Wang, W., * and Shields, J., Enzyme-linked immunosorbent assay for the detection of pathogenic spiroplasma in commercially exploited crustaceans from China. 2009. Aquaculture. 292:166-171.

  29. Wang, W. *, Gu, W., Gasparich, G.,Bi, K., Ou, J., Meng, Q., Liang, T., Feng, Q., Zhang, J., and Zhang, Y., Spiroplasma eriocheiris sp. nov., a novel species associated with mortalities in Eriocheir sinensis, Chinese mitten crab. 2010. Int J Syst Evol Microbiol, 61:703-708

     

    通讯地址:江苏省南京市栖霞区文苑路1号,南京师范大学 生命科学学院 分子细胞生物学研究所

    邮编:210023

    Email: tmliang@njnu.edu.cn

     

    (2017年4月更新)