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李建宏

李建宏, 男,19639月出生,理学博士,教授,博士生导师。

学习经历:1981~1985年南京大学生物系植物专业本科;1985~1988年南京大学生物系硕士;1988~1991年工作于中科院南京地理与湖泊研究所;11991~1995年南京大学生物系博士;2000~2002年法国国家科学研究中心细菌化学研究所(L.C.B.- C.N.R.S)博士后。1995年至今工作于南京师范大学生命科学学院。
    科研及成果:近年来主持国家自然科学基金、江苏省自然基金等多项科研项目,以及来自多个合作单位委托的课题。曾获国家海洋局科技创新二等奖、校青年骨干教师等奖励。发表论文60余篇。

社会兼职:现(曾)任江苏省植物生理学会理事、江苏省生态学会理事、江苏省毒理学会理事;《湖泊科学》、《植物科学学报》编委。

主要的研究兴趣:1)微藻与水环境:研究水生态系统中微藻, 特别是形成水华的有毒有害蓝藻的生理生态,探索水华发生规律,为有毒蓝藻的控制提供理论基础。(2)蓝藻细胞学研究:探索蓝藻细胞的重要代谢过程及机理;以蓝藻作为表达反应器,表达外源有用基因。(3 微藻资源的利用:筛选各种具有应用前景的微藻,探索藻类的大量培养及应用技术。

通讯联系 E-mail: lijianhong@njnu.edu.cn

代表文章(* 为通讯作者):

 

 

 

  • Hong S.J., Q.H. Pan, S.Y. Chen, Y. Zu, C.X. Xu, J.H. Li*. Identification and characterization of alkaline phosphatase gene phoX in Microcystis aeruginosa PCC7806. 3 Biotech  11:218. 2021.
  • Zu Y., S.J. Hong, C.X. Xu, W.W. Li, S.Y. Chen, J.H. Li*. Cell wall surface layer (S-layer) promotes colony formation in Microcystis: comparison of S-layer characteristics between colonial and unicellular forms of Microcystis and function conformation. Eenviron Sci Pollut Res 27:42254–42263. 2020.
  • Xu C.X., X.Q. LiuY. LiuX. ZhangC.Z. Zhang, J.H. Li*, X.J. Liu*. High sensitive single chain variable fragment screening from a microcystin-LR immunized mouse phage antibody library and its application in immunoassay. Talanta 197:397-405. 2019.
  • Xu C.X., W.J. Miao, Y. He, Y. Zu, X.Q. Liu, J.H. Li*, X.J. Liu*. Construction of an immunized rabbit phage display antibody library for screening microcystin-LR high sensitive single-chain antibody. Int J Biol  Macromol  123:369–378. 2019.
  • Xu C.X., Y. Yang, L.W. Liu, J.H. Li*, X.Q. Liu, X. Zhang, Y. Liu, C.Z. Zhang, X.J. Liu. Microcystin-LR nanobody screening from an alpaca phage display nanobody library and its expression and application. Ecotox  Environ Safe  151: 220–227. 2018.
  • Li W.W.M.S. XiaW.B. LiL.W. LiuJ.H. Li* . Characterization of a Putative S-layer Protein of a Colonial Microcystis Strain. Curr Microbiol 75:173–178. 2018.
  • Liu C., L.J. Li, C.Y. Wu, K. N. Guo, J.H. Li*,Growth and antioxidant production of Spirulina in ,different NaCl concentrations. Biotechnol Lett 38:1089-1096. 2016.
  • LiS.SJ.H. Li*M.S. XiaH. Zhang, Adsorption of nitrogen and phosphorus by intact cells and cell wall polysaccharides of Microcystis XW01. J Appl Phyco 25:1539-1544. 2013
  • Wang, Y.W., J. Zhao, J.H. Li*, S.S. Li, L.H. Zhang, M. Wu, Effects of calcium levels on colonial aggregation and buoyancy of Microcystis aeruginosa. Curr Microbiol 62:679-683. 2011.
  • Hua, X.H., J.H. Li*, J.J. Li, L.H. Zhang, Y. Cui, Selective inhibition of the cyanobacterium, Microcystis, by a Streptomyces sp. Biotechnol Lett 31:1531-1535. 2009.
  • Cui, Y., J.H. Li*, J.J. Li, J. Wang, Y.P. Weng, A heterotrophic nanofagellate grazing on the toxic cyanobacterium Microcystis aeruginosa. Ann Limnol (Int J Lim) 45(1):1-6. 2009.
  • Wang, Y., J.H. Li*, L. Fu, M. Wu, Y.P. Weng, Y.M. Zhou, Effects of different iron concentrations on the growths of a unicellular strain and a colonial strain of Microcystis aeruginosa. Enviro Sci 30(1): 241-246. 2009.
  • Lei, S., J.H. Li, Y. Cheng, L. Wang, W.L. Chen, C.C. ZhangTwo genes encoding protein kinases of the HstK family are involved in synthesis of the minor heterocyst- specific glycolipid in the cyanobacterium Anabaena sp. strain PCC 7120. J Bacteriol 189 (14): 5075-81. 2007.
  • Cheng, Y., J.H. Li, L. Shi, L. Wang, A. Latifi and C.C. Zhang, A pair of iron-responsive genes encoding protein kinases with a Ser/Thr-kinase domain and a His-kinHis-kinase domain are regulated by NtcA in the cyanobacterium Anabaena sp. strain PCC 7120. J Bacteriol 188(13):4822-4829. 2006.
  • Li, J.H., S. Laurent, V. Konde and C.C. ZhangAn increase in the level of 2-oxoglutarates heterocyst development in the cyanobacterium Anabaena PCC 7120. Microbiology 149:3257-3263. 2003.
  • Wang, L., Y.P. Sun, W.L. Chen, J.H. Li, C.C. Zhang, Genomic analysis of protein kinases, protein phosphatases and two-component regulatory systems of the cyanobacterium Anabaena sp. PCC 7120. FEMS Lett 217:155-65. 2002.
  • Phalip V., J.H. Li and C.C. ZhangHstK, a cyanobacterial protein with both a Ser/Thr kinase domain and a His-kinase domain: implication for the mechanism of signal transduction. Biochem J 360:639-644. 2001.